2025, Vol. 8, Issue 3, Part B

Purpose: In cases of gliomas (intracranial and spinal), fewer studies have attempted the histopathological and imaging grade correlation. We thus aim to assess the sensitivity and specificity of conventional imaging techniques for the same.

Materials and Methods: The study comprised of 40 patients referred to the department of Radio-diagnosis at a tertiary care hospital in Ahmedabad, India, for a period of 24 monts, with a clinical suspicion of Neuraxial tumour. Computed Tomography and Magnetic Resonance Imaging of the neuraxis was performed.

Results: The mean age of patients was 33 ± 5.68 years with a male predominance (M:F ratio-1.5:1). The major presenting complaint was headache (82.5%). Dorsal spine (10%) was the most commonly affected in spinal gliomas, whereas Parietal lobe was the most common site affected (40%) intracranially. Major imaging findings included soft tissue with variable contrast enhancement and cystic components in 95% of the patients, with the most common ancillary finding being edema (65%) followed by mass effect (60%) depending on the type of tumour. MRI was found to have a better overall sensitivity and specificity in grading of gliomas as compared to CT and was highest for grade IV tumours in both modalities (90.00% and 96.88% for CT and 90.00% and 96.67% for MRI in grade IV). Edema (52.94%), contrast enhancement (47.06%) and multifocality (47.06%) were poor prognostic indicators.