AbstractBackground: Pancreatic adenocarcinoma is one of the most competitive and deadly malignancies globally. Early analysis and correct staging are crucial for enhancing treatment consequences and survival fees. Multimodal imaging strategies, especially computed tomography (CT), play a pivotal function in the detection, staging, and control of pancreatic most cancers. However, CT imaging should be included with other diagnostic techniques, inclusive of laboratory assessments and scientific critiques, to ensure comprehensive patient care. This take a look at objectives to evaluate the efficacy of CT imaging in detecting and staging pancreatic adenocarcinoma and to explore its medical implications in remedy making plans.
Objective: The primary objective of this observe turned into to assess the diagnostic overall performance of CT imaging in staging pancreatic adenocarcinoma, that specialize in its potential to stumble on the tumor's quantity, vascular involvement, and respectability. Additionally, the take a look at aimed to research the position of CT in helping clinicians in determining the maximum appropriate remedy alternatives for patients with pancreatic most cancers.
Methodology: This retrospective study was conducted at Tikrit Teaching Center from December 2023 to December 2024 with 250 patients diagnosed with pancreatic cancer included in this study All patients received computed tomography as part of the initial diagnosis. CT scans are analyzed in a variety of environment including blood vessels pancreatic tissue and lymph nodes To assess tumor size, location, and vascular invasion and spread Including clinical information Laboratory results (including serum CA 19-9 levels) and physical examination to better understand each patient's status. The results of this study were compared with histopathological and surgical results when available.
Results: The study included 250 patients with a median age of 65 years (range: 45-85), of whom 54% were men and 46% were Women, the majority of patients had advanced pancreatic cancer (Tables 3 and 4). CT imaging correctly identified the tumor in 94% of cases, with sensitivity in identifying vascular invasion and metastasis. The accuracy of CT in detecting tumor extent is 82%, and diagnostic sensitivity increases when combined with CA 19-9 levels. Imaging findings correlate well with surgical and anatomical results. This is especially true in patients with localized disease.
Conclusion: CT imaging is a important device in diagnosing and staging pancreatic adenocarcinoma, providing excessive sensitivity in detecting tumor size, vascular invasion, and metastasis. It plays a vital position in assessing tumor respectability and guiding treatment decisions. Combining CT with laboratory markers like CA 19-9 complements diagnostic accuracy and assists in early detection, although challenges remain due to the typically advanced stage at prognosis.
