AbstractBackground:Integrating multi-parametric magnetic resonance imaging (MRI) into a program for detection appears to be the most effective method for enhancing the early diagnosis of prostate cancer (P Ca). The objective of this study was to evaluate the utility of MRI in the diagnosis and classification of P Ca.
Methods: This study was conducted on a sample of 30 male patients, aged between 65 and 84 years old, using a cross-sectional descriptive study, with elevated prostate-specific antigen for diagnosis and known P Ca patients for grading, all having no contraindication to MRI. Patients were subjected toMRI examination and Trans-rectal ultrasound guided biopsy.
Results: There was no significant correlation between apparent diffusion coefficient (ADC) and other variables. The best cutoff point of ADC to identify cases with clinically significant lesions was > 0.633 mm2/s x10-3 with 77.3% sensitivity and 62.5% specificity. There was significant difference between the clinically significant and clinically insignificant cases regarding the distribution of the prostate imaging-reporting and data system (PIRADS) categories (p< 0.001). There was significant difference between the Gleason score (GS) categories regarding the distribution of the PIRADS categories (P = 0.002).
Conclusion: The trans-rectal ultrasound biopsy is the established clinical standard for definitively diagnosing prostate cancer. MRI plays a crucial role in enhancing the safety of diagnostic procedures. Additionally, it can assist in the process of staging, as well as in the planning of surgery or radiation treatment. Furthermore, the incorporation of multi-parametric MRI and diffusion weighted imaging into a diagnostic program enhances the accuracy of the diagnosis.
